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AMLONG-10

Original price was: ₹81.00.Current price is: ₹65.00.

Class: Antihypertensive (CCB + ARB combination)

Uses:

  • Hypertension (high blood pressure)

  • Reduces risk of heart attack and stroke

Mechanism of Action:

  • Amlodipine: Relaxes blood vessels by blocking calcium entry into smooth muscle.

  • Olmesartan: Blocks angiotensin II receptors → prevents vasoconstriction and aldosterone release.

Dose: Usually once daily (as prescribed)

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Description

1. Introduction

Amlong-1O is a fixed-dose combination antihypertensive drug containing amlodipine and olmesartan. It is used when single-drug therapy does not adequately control blood pressure.


2. Pharmacological Classification

  • Amlodipine: Dihydropyridine calcium channel blocker

  • Olmesartan: Angiotensin II receptor blocker (ARB)


3. Mechanism of Action

Amlodipine:

  • Inhibits L-type calcium channels in vascular smooth muscle

  • Causes peripheral vasodilation

  • Decreases peripheral resistance

Olmesartan:

  • Selectively blocks AT₁ receptors

  • Prevents action of angiotensin II

  • Reduces vasoconstriction and aldosterone secretion

  • Lowers blood pressure

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