DYNAGLIPT M
Original price was: ₹132.00.₹106.00Current price is: ₹106.00.
Composition:
Dynaglipt M is a combination of Sitagliptin (DPP-4 inhibitor) and Metformin (biguanide).Use:
Used for type 2 diabetes mellitus to control blood sugar when diet and exercise alone are insufficient.
Description
1. Pharmacology:
Sitagliptin:
Mechanism: Inhibits dipeptidyl peptidase-4 (DPP-4) → prolongs action of incretin hormones → increases glucose-dependent insulin secretion, decreases glucagon.
Effect: Reduces postprandial and fasting blood glucose.
Metformin:
Mechanism: Decreases hepatic gluconeogenesis, increases peripheral glucose uptake, reduces intestinal glucose absorption.
Effect: Lowers fasting blood sugar, improves insulin sensitivity.
2. Indications:
Type 2 diabetes mellitus inadequately controlled with lifestyle modifications.
Often used in patients who need dual therapy to achieve glycemic targets.
3. Dosage and Administration:
Typically once or twice daily with meals to reduce gastrointestinal side effects.
Dose depends on renal function, age, and glycemic control.
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