METOPOLE-50 XL
Original price was: ₹65.00.₹52.00Current price is: ₹52.00.
Brand Example: Metoprol-XL, Lopressor XL
Formulation: Extended-release (XL) tablet, 50 mg
Class: Beta-1 selective beta-blocker.
Description
1. Pharmacology
Class: Beta-adrenergic blocker, cardioselective (beta-1 selective).
Mechanism: Blocks beta-1 receptors → decreases sympathetic stimulation → lowers heart rate, myocardial contractility, and oxygen demand → reduces blood pressure and improves survival in heart failure.
Pharmacokinetics:
Absorption: Slowly absorbed due to XL formulation → stable blood levels for 24-hour coverage.
Metabolism: Hepatic (CYP2D6).
Excretion: Mainly renal (metabolites).
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